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KMID : 0376419800040010187
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Chonbuk University Medical Journal
1980 Volume.4 No. 1 p.187 ~ p.193
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A Study on Enzyme Acitities of the Patholgic mucous membrane of the Maxillary sinus.
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Abstract
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For the establishment of the knowledge of enzyme activities of the pathologic mucosa, attempts were made to investigate the enzyme activities such as phosphatases, transaminases, ATPase and Adenosine deaminase(ADA) in the pathologic mucosa of the chronic sinusitis, maxillary polyposis, maxillary mucocele and nasal polyposis using the normal maxillary mucosa as control.
The results of this study were as follows ;
1. Alkaline phosphatase activities of the normal mucosa, mucocele and maxillary polyp were similarly appeared. But in the nasal polyposis and in the chronic maxillary sinusitis the enzyme- acitivities were appeared 16% and 50% compared to that of control.
2. GPT activity was very low in the nasal polyposis, maxillary mucocele and normal mucosa. In the maxillary polyposis the enzyme activities were 5 unit/mg protein and 7 unit/mg protein.
3. ATPase showed nearly the same activity both in pathologic and normal maxillary mucosa, in the nasal polyposis the enzyme activity was relatively lower than that of the otheres.
4. The patterns of the relative activities of acid phosphatase, GOT and ADA were similar in each experimental materal. Especially all the experimental enzyme activities were detected much lower in nasal polyp and mucecele compared to the others.
S. The further study of these results which show us that the activities of all the above enzymes in the maxillary polyp were much higher than those of nasal polyp may bring us the good indication for the better understanding of the pathogenesis of these diseases in the biochemical aspect.
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KEYWORD
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